New Lewatit ion exchange resins and adsorbers for separation, purification, and chromatography of biomolecules
The quality control laboratory of LANXESS’s Liquid Purification Technologies business unit verifies the ion exchange and adsorber resins according their specification during production. Photo: LANXESS
Specialty chemicals company LANXESS has grouped together 16 new ion exchange resins and absorbents for the pharmaceutical and bioprocessing industries under its trusted umbrella brand Lewatit. They are used in various pharmaceutical and bioprocessing applications to separate and purify biomolecules. Applications of these end products range from food and animal feeds to active pharmaceutical ingredients (APIs) that are used in medicinal products.
“Typically, our products support the separation of biomolecules from complex biomass mixtures and play a key role in their further purification or stabilization,” explained Dr. Jenny Boettger, Technical Marketing Manager in the Liquid Purification Technologies (LPT) business unit at LANXESS. “As one of the leading manufacturers of ion exchange resins, we are hoping that this innovative product range will attract new customers from the pharmaceutical and bioprocessing industries and further strengthen our market position,” added the chemist.
The production of biomolecules derived from natural extracts and biological fermentation processes is strongly supported by a wide range of Lewatit ion exchange and adsorber resins. This resin technology opens up a variety of separation and purification options for all kinds of operation scales. The new types are specifically designed to be used in downstream processing for production of various biomolecules, including products from animal- and plant-sourced natural extracts. All resins are based on hydrophobic (polystyrene-divinylbenzene) or medium hydrophilic (polyacrylic) polymers. They were specifically developed to meet the high demands in industries such as biotechnology, pharmaceuticals, biopharmaceuticals, nutraceuticals, and food production in order to detoxify, convert, decolorize, or demineralize the respective molecules more easily.
Through ion exchange or adsorption processes, biomolecules such as peptides, antibiotics, vitamins, amino acids, and polysaccharides can be separated and purified more effectively. All these biomolecules are indispensable in today’s world. Antibiotics are essential for the treatment of bacterial infectious diseases. The intake of vitamins and numerous amino acids and proteins supports vital functions of the body. Diverse polysaccharides are found in part in everyday use. In the form of heparin and structure-like polysaccharides, for example, they are used to prevent venous thrombosis. In cosmetics, hyaluronic acid acts as a humectant due to its high water-binding capacity.
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