Biotium, a leader in life science reagents, unveiled TyraMax Amplification Dyes and Kits, a next-generation solution set to redefine tyramide signal amplification (TSA) for spatial biology and multiplex fluorescence imaging.

TyraMax dyes are engineered for unmatched brightness, photostability, and stability in amplification buffer, outperforming existing competitor reagents. With the widest color selection on the market—from blue to near-infrared—researchers can design complex spectral panels with unprecedented flexibility.

All TyraMax dyes, including near-IR options, remain chemically stable in amplification buffer for at least 24 hours, making them ideal for automated staining workflows and resistant to oxidation. When combined with TSA, TyraMax dyes deliver up to 100-fold higher detection sensitivity than conventional immunofluorescence, while maintaining crisp, photostable signals for demanding workflows such as cyclic immunofluorescence (CycIF).

“Advances in spatial analysis are transforming our understanding of complex biology, but many methods still rely on underperforming probes. TyraMax dyes give researchers the brightness, stability, and panel flexibility they need to push spatial biology forward,” said Lori Roberts, Director of Bioscience at Biotium.

TyraMax 740/770 stands out for exceptional brightness, photostability, and working solution stability, making it a perfect fit for automated workflows. Across the board, TyraMax dyes outperform leading competitors, including Thermo Fisher’s Aluora Spatial Dyes and Akoya Biosciences’ Opal Polaris, all at a more accessible price point.